Ibuprofen is a non-steroidal and anti-inflammatory drug that is used in many different over-the-counter medicines that treat fever, arthritis, cramps and general aches.<br>
This drug was first created and developed by the Boots Group, one of the major pharmaceutical companies in the United Kingdom. The scientists Stewart Adams, John Nicholson, and Colin Burrows developed the drug, and a patent for it was filed in 1961. The drug was originally created for the treatment of rheumatoid arthritis in the UK in 1969.<br>
In the United Kingdom, ibuprofen was available for prescription beginning in 1969. In the United States, it was available by prescription in 1974. It wasnt until ten years later, in 1984, that the drug was available via over-the-counter in the United States.<br>
Since the drug has been over-the-counter, the number of cases recorded for overdoses of ibuprofen has been great and quite common. The cases of overdoses have shown that the response of an ibuprofen overdose have included abdominal pain, nausea, vomiting, drowsiness, dizziness, headache, respiratory depression, gastrointestinal bleeding, seizures, hypertension, and even cardiac arrest.<br>
However, the sensitivity to large doses of ibuprofen ranges greatly. The recommend dosage of ibuprofen has a maximum limit of 1,200 mg every 24 hours. Sometimes, doctors, depending on special circumstances, can even prescribe a maximum amount of ibuprofen to 3,200 mg (but this is in rare, special cases). The recommended dosage for ibuprofen in the United States is 200 to 400 mg every four to six hours.<br>
Despite this, doses vary in different countries. In Spain dosages as high as 600 mg are regularly available. In Germany dosages of 600 mg are available by prescription, while dosages of 400 mg are available over-the-counter. In Mexico, though, you can find ibuprofen in dosages as high as 800 mg.<br>
Ibuprofen is most commonly administered in pill form. Yet, it can be taken in other forms. It is also available in a topical form that is absorbed through the skin, which is usually taken for sports injuries and other injuries that have become swollen.<br>
In Europe, Australia, and New Zealand, ibuprofen lysine has been created as to give the drug to patients intravenously (by needle).<br>
Studies have shown that ibuprofen may be very useful in the treatment of Alzheimers disease. It has also been shown in research that taking the drug on a regular basis can delay or even prevent Parkinsons disease.<br>
Today, the drug has many international trade names. Its Advil and Brufen in Spain, Bupuren in South Korea, Eve in Japan, Ibufen in Iceland, Ibumax, Motrin and Panafen in Finland, Dalsy in Brazil, and Neofen in Croatia, among many other names in many other countries around the world.<br>
Ibuprofen is now as commonly used as other over-the-counter pills used for the same problems. Ibuprofen competes for the top position with aspirin and acetaminophen.
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About the Author:
Amber Singleton is a writer for Biotek Pharmaceuticals, Inc. Biotek specializes in over-the-counter drugs, http://www.biotekpharm.com/default.php?cPath=5">energy supplements and dietary supplements focusing on the health conscious consumer. They offer a wide selection of both over-the-counter drugs and dietary supplements, like http://www.biotekpharm.com/product_info.php?cPath=7&products_id=20">Spanish Fly, of the highest quality. They are a FDA and DEA regulated company.
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